EdenteV2, Main, Exploration, bibRecord, 00C027

Active peptides in the skins of two hundred and thirty American amphibian species

Identifieur interne : 00C027 ( Main/Exploration ); précédent : 00C026; suivant : 00C028

Active peptides in the skins of two hundred and thirty American amphibian species

Auteurs : V. Erspamer ; G. Falconieri Erspamer ; J. M. Cei [Argentine]

Source :

Comparative Biochemistry and Physiology, Part C: Comparative Pharmacology [ 0306-4492 ] ; 1988.

RBID : ISTEX:D48B434AA053010E26649DF8B1775116AAF2A822

Descripteurs français

Wicri :
- geographic : Argentine, Chili, Équateur, Pérou.
- topic : Méthanol.

English descriptors

KwdEn :
- Active peptides, American amphibians, Amphibian, Amphibian skin, Amphibian skin peptides, Amphibian species, Anastasi, April, Argentina, August, Average weight, Bioassay, Biogenic amines, Blood pressure, Bombesins, Brad, Bradykinin, Bradykinins, Bufo, Caer, Caerulein, Chile, Costa, Dermorphin, Dermorphins, Ecuador, Erspamer, Falconieri, Falconieri erspamer, Fresh skin, Frog, Hyla, Hylid frogs, Janeiro, July, June, Leptodactylus, Melchiorri, Methanol, Methanol extracts, Montecucchi, Napo, Parallel bioassay, Peptide, Peptide families, Peptide molecules, Peptide protein, Peptides skin, Personal communication, Peru, Pharmac, Pharmacological actions, Phyllokinin, Phyllomedusa, Phyllomedusa bicolor, Phyllomedusa sauvagei, Phyllomedusa sauvagei skin, Phyllomedusid, Phyllomedusid frogs, Phyllomedusin, Phys, Physalaemin, Physalaemus, Pleurodema, Rana, Rica, Rohdei, Rohdeilitorin, Sauvagei, Sauvagine, Sept, Skin, Skin extracts, Smilisca, Spinulosus, Subfamily, Tachykinins, Telmatobius, Trypt, Tucuman, Whole bodies, Whole body.
Teeft :
- Active peptides, American amphibians, Amphibian, Amphibian skin, Amphibian skin peptides, Amphibian species, Anastasi, April, Argentina, August, Average weight, Bioassay, Biogenic amines, Blood pressure, Bombesins, Brad, Bradykinin, Bradykinins, Bufo, Caer, Caerulein, Chile, Costa, Dermorphin, Dermorphins, Ecuador, Erspamer, Falconieri, Falconieri erspamer, Fresh skin, Frog, Hyla, Hylid frogs, Janeiro, July, June, Leptodactylus, Melchiorri, Methanol, Methanol extracts, Montecucchi, Napo, Parallel bioassay, Peptide, Peptide families, Peptide molecules, Peptide protein, Peptides skin, Personal communication, Peru, Pharmac, Pharmacological actions, Phyllokinin, Phyllomedusa, Phyllomedusa bicolor, Phyllomedusa sauvagei, Phyllomedusa sauvagei skin, Phyllomedusid, Phyllomedusid frogs, Phyllomedusin, Phys, Physalaemin, Physalaemus, Pleurodema, Rana, Rica, Rohdei, Rohdeilitorin, Sauvagei, Sauvagine, Sept, Skin, Skin extracts, Smilisca, Spinulosus, Subfamily, Tachykinins, Telmatobius, Trypt, Tucuman, Whole bodies, Whole body.

Abstract

Abstract: 1. 1. Extracts prepared from dried or fresh skins of more than 200 American amphibian species were subjected to biological screening in order to determine occurrence and contents of peptides active on smooth muscle preparations, systemic blood pressure and, subordinately, external secretions, anterior pituitary and the central nervous system. 2. 2. The peptide families identified in skin extracts were as follows: caruleins (caerulein, phyllocaerulein), tachykinins (physalaemin, phyllomedusin), bombesins (phyllolitorin, [Leu8]phyllolitorin, rohdeilitorin), bradykinins (phyllokinin and others), sauvagine, dermorphins (dermorphin, [Hyp6]dermorphin), tryptophyllins (numerous peptides) and, finally, miscellaneous peptides. None of the above peptide families showed a widespread distribution, but all were restricted to particular amphibian genera or stocks. 3. 3. The hylid frogs of the Phyllomedusinae family occupy a unique position, as their skin displayed the greatest variety and abundance of active peptides ever found in any amphibian stock in the world. 4. 4. The array of peptide molecules occurring in the skin of the American amphibians is destined to increase because numerous other peptide molecules await isolation, elucidation of structure and definition of possible biological activities.

Url:

https://api.istex.fr/document/D48B434AA053010E26649DF8B1775116AAF2A822/fulltext/pdf

DOI: 10.1016/0742-8413(86)90063-0

Affiliations:

Argentine

Links toward previous steps (curation, corpus...)

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to stream Istex, to step Curation: 006970
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to stream Main, to step Curation: 00C027

Le document en format XML

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<author><name sortKey="Erspamer, V" sort="Erspamer, V" uniqKey="Erspamer V" first="V." last="Erspamer">V. Erspamer</name>
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<author><name sortKey="Erspamer, G Falconieri" sort="Erspamer, G Falconieri" uniqKey="Erspamer G" first="G. Falconieri" last="Erspamer">G. Falconieri Erspamer</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Active peptides</term>
<term>American amphibians</term>
<term>Amphibian</term>
<term>Amphibian skin</term>
<term>Amphibian skin peptides</term>
<term>Amphibian species</term>
<term>Anastasi</term>
<term>April</term>
<term>Argentina</term>
<term>August</term>
<term>Average weight</term>
<term>Bioassay</term>
<term>Biogenic amines</term>
<term>Blood pressure</term>
<term>Bombesins</term>
<term>Brad</term>
<term>Bradykinin</term>
<term>Bradykinins</term>
<term>Bufo</term>
<term>Caer</term>
<term>Caerulein</term>
<term>Chile</term>
<term>Costa</term>
<term>Dermorphin</term>
<term>Dermorphins</term>
<term>Ecuador</term>
<term>Erspamer</term>
<term>Falconieri</term>
<term>Falconieri erspamer</term>
<term>Fresh skin</term>
<term>Frog</term>
<term>Hyla</term>
<term>Hylid frogs</term>
<term>Janeiro</term>
<term>July</term>
<term>June</term>
<term>Leptodactylus</term>
<term>Melchiorri</term>
<term>Methanol</term>
<term>Methanol extracts</term>
<term>Montecucchi</term>
<term>Napo</term>
<term>Parallel bioassay</term>
<term>Peptide</term>
<term>Peptide families</term>
<term>Peptide molecules</term>
<term>Peptide protein</term>
<term>Peptides skin</term>
<term>Personal communication</term>
<term>Peru</term>
<term>Pharmac</term>
<term>Pharmacological actions</term>
<term>Phyllokinin</term>
<term>Phyllomedusa</term>
<term>Phyllomedusa bicolor</term>
<term>Phyllomedusa sauvagei</term>
<term>Phyllomedusa sauvagei skin</term>
<term>Phyllomedusid</term>
<term>Phyllomedusid frogs</term>
<term>Phyllomedusin</term>
<term>Phys</term>
<term>Physalaemin</term>
<term>Physalaemus</term>
<term>Pleurodema</term>
<term>Rana</term>
<term>Rica</term>
<term>Rohdei</term>
<term>Rohdeilitorin</term>
<term>Sauvagei</term>
<term>Sauvagine</term>
<term>Sept</term>
<term>Skin</term>
<term>Skin extracts</term>
<term>Smilisca</term>
<term>Spinulosus</term>
<term>Subfamily</term>
<term>Tachykinins</term>
<term>Telmatobius</term>
<term>Trypt</term>
<term>Tucuman</term>
<term>Whole bodies</term>
<term>Whole body</term>
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<keywords scheme="Teeft" xml:lang="en"><term>Active peptides</term>
<term>American amphibians</term>
<term>Amphibian</term>
<term>Amphibian skin</term>
<term>Amphibian skin peptides</term>
<term>Amphibian species</term>
<term>Anastasi</term>
<term>April</term>
<term>Argentina</term>
<term>August</term>
<term>Average weight</term>
<term>Bioassay</term>
<term>Biogenic amines</term>
<term>Blood pressure</term>
<term>Bombesins</term>
<term>Brad</term>
<term>Bradykinin</term>
<term>Bradykinins</term>
<term>Bufo</term>
<term>Caer</term>
<term>Caerulein</term>
<term>Chile</term>
<term>Costa</term>
<term>Dermorphin</term>
<term>Dermorphins</term>
<term>Ecuador</term>
<term>Erspamer</term>
<term>Falconieri</term>
<term>Falconieri erspamer</term>
<term>Fresh skin</term>
<term>Frog</term>
<term>Hyla</term>
<term>Hylid frogs</term>
<term>Janeiro</term>
<term>July</term>
<term>June</term>
<term>Leptodactylus</term>
<term>Melchiorri</term>
<term>Methanol</term>
<term>Methanol extracts</term>
<term>Montecucchi</term>
<term>Napo</term>
<term>Parallel bioassay</term>
<term>Peptide</term>
<term>Peptide families</term>
<term>Peptide molecules</term>
<term>Peptide protein</term>
<term>Peptides skin</term>
<term>Personal communication</term>
<term>Peru</term>
<term>Pharmac</term>
<term>Pharmacological actions</term>
<term>Phyllokinin</term>
<term>Phyllomedusa</term>
<term>Phyllomedusa bicolor</term>
<term>Phyllomedusa sauvagei</term>
<term>Phyllomedusa sauvagei skin</term>
<term>Phyllomedusid</term>
<term>Phyllomedusid frogs</term>
<term>Phyllomedusin</term>
<term>Phys</term>
<term>Physalaemin</term>
<term>Physalaemus</term>
<term>Pleurodema</term>
<term>Rana</term>
<term>Rica</term>
<term>Rohdei</term>
<term>Rohdeilitorin</term>
<term>Sauvagei</term>
<term>Sauvagine</term>
<term>Sept</term>
<term>Skin</term>
<term>Skin extracts</term>
<term>Smilisca</term>
<term>Spinulosus</term>
<term>Subfamily</term>
<term>Tachykinins</term>
<term>Telmatobius</term>
<term>Trypt</term>
<term>Tucuman</term>
<term>Whole bodies</term>
<term>Whole body</term>
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<term>Chili</term>
<term>Équateur</term>
<term>Pérou</term>
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<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Méthanol</term>
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<front><div type="abstract" xml:lang="en">Abstract: 1. 1. Extracts prepared from dried or fresh skins of more than 200 American amphibian species were subjected to biological screening in order to determine occurrence and contents of peptides active on smooth muscle preparations, systemic blood pressure and, subordinately, external secretions, anterior pituitary and the central nervous system. 2. 2. The peptide families identified in skin extracts were as follows: caruleins (caerulein, phyllocaerulein), tachykinins (physalaemin, phyllomedusin), bombesins (phyllolitorin, [Leu8]phyllolitorin, rohdeilitorin), bradykinins (phyllokinin and others), sauvagine, dermorphins (dermorphin, [Hyp6]dermorphin), tryptophyllins (numerous peptides) and, finally, miscellaneous peptides. None of the above peptide families showed a widespread distribution, but all were restricted to particular amphibian genera or stocks. 3. 3. The hylid frogs of the Phyllomedusinae family occupy a unique position, as their skin displayed the greatest variety and abundance of active peptides ever found in any amphibian stock in the world. 4. 4. The array of peptide molecules occurring in the skin of the American amphibians is destined to increase because numerous other peptide molecules await isolation, elucidation of structure and definition of possible biological activities.</div>
</front>
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Active peptides in the skins of two hundred and thirty American amphibian species

Active peptides in the skins of two hundred and thirty American amphibian species

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri